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Urolithin A

Updated 3/11/2026
7.2Rating
Longevity
Muscle
Performance
Inflammation
Immune
Energy
Metabolism

Research Summary

Urolithin A is a first-in-class postbiotic metabolite produced by the gut microbiome from ellagitannins and ellagic acid, polyphenols naturally found in pomegranates, strawberries, and walnuts. Since only an estimated 40% of the population possesses the specific gut flora required to synthesize it, supplementation has become the primary method to ensure therapeutic concentrations. It is widely recognized in longevity science for its unique ability to rejuvenate cellular health.

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